Being rich in polyphenols and flavonoids, tamarind has been shown to decrease LDL cholesterol and increase HDL cholesterol, thereby lowering the risk of atherosclerosis. The dried pulp was also found to have anti-hypertensive effects, reducing diastolic blood pressure.void taking tamarind along with anti-inflammatory drugs. Tamarind is also found to increase the bioavailability of the antiplatelet drug aspirin, thus increasing the absorption of aspirin in the blood. So avoid consuming tamarind if you are on antiplatelet drugs like aspirin.